![]() ![]() ![]() Objective cough frequency was significantly correlated with reported cough scores using visual analogue scale (rs=0.43, bias-corrected 95%CI 0.25, 0.56) and verbal categorical description day-time score (rs=0.39, bias-corrected 95%CI 0.22, 0.54).Ĭough characteristics alone are not distinct enough to accurately differentiate between common acute respiratory illnesses in children.ĭespite the efforts of research groups to develop and implement at least partial automation, cough counting remains impractical. Inter-rater agreement in cough type (wet/dry) between blinded observers was almost perfect (қ=0.89, 95%CI 0.81, 0.97). Among diagnoses, specificity (8-74%) and sensitivity (53-100%) varied. Overall agreement in diagnosis between the respiratory specialist and discharge diagnosis was slight (қ=0.13, 95%CI 0.03, 0.22). In those with respiratory illnesses, caregiver reported cough scores and wet cough (range 42-63%) was similar. Caregiver reported cough scores were related with objective cough frequency using Spearman’s coefficient (rs).Ī cohort of 148 children (n=118 with respiratory illnesses, n=30 controls), median age=2.0 years (interquartile range 0.7, 3.9), 58% males, and 50% First Nations children were enrolled. Cough scored by a respiratory specialist was compared to discharge diagnosis using agreement (Cohen’s kappa coefficient ), sensitivity, and specificity. Cough sounds and type were assessed independently by two observers blinded to the clinical data. ![]() Coughs were extracted and frequency defined (coughs/hour). Spontaneous coughs were digitally recorded over 24-hours except for the controls, who provided three voluntary coughs. ![]() Cough is a common symptom in these childhood respiratory illnesses but there is currently no large cohort data on whether various cough characteristics can differentiate between these aetiologies.Ĭan various clinically-based cough characteristics (frequency, the sound itself, or type ) be used to differentiate common aetiologies (asthma, bronchiolitis, pneumonia, other acute respiratory infections) of acute cough in children?īetween 2017-2019, children aged 2-weeks to ≤16-years hospitalised with asthma, bronchiolitis, pneumonia, other acute respiratory infections, or controls were enrolled. Acute respiratory illnesses cause substantial morbidity worldwide. ![]()
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